Sam-E Explained

Sam-E Explained



S-Adenosyl-L-methionine (also called S-adenosyl methionine, S-adenosylmethionine, SAMe, or SAM-e in the United States or ademetionine in Europe, and also often abbreviated as SAM and AdoMet) is a chemical that is found naturally in the body. SAMe is sold in the United States as a dietary supplement. SAMe was discovered in the early 1950s.


SAM-e has only been available as an over the counter dietary supplement in the US since 1999, but it has been used as a prescription drug in Italy since 1979, Spain since 1985, and Germany since 1989. SAM-e is most commonly used for treatment of depression, osteoarthritis, fibromyalgia and liver disease.


Brown explained that SAM-e is produced in the body from methionine, a sulfur-containing amino acid, and the energy-producing compound adenosine triphosphate. SAM-e is a physiologically essential compound, he said, adding that some chemists believe it ranks with adenosine triphosphase (ATP) as a pivotal molecule in living cells.


SAM-e – Nootropics Expert, SAM-e – Nootropics Expert, SAM-e (S-adenosylmethionine, SAMe): Supplement for …


SAM-e (S-adenosylmethionine, SAMe): Supplement for …


S-Adenosyl-L-homocyst…, Glutathione, 5-Hydroxytryptophan, Tetrahydrofolic acid, Pyridoxal phosphate

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